Explanation of Term asthma Pathophysiology


Pathophysiology is the study of what is normal, or what causes normal physiological processes to interfere. Asthma is a chronic inflammatory disease problems in the lungs and bronchioles characterized by reversible bronchospasm that often result from an exaggerated response to various stimuli. This is a physiological response of the lungs take when attacked by allergens.

What does this mean? Well firstly it means that asthma is not all in the mind and it can not be outgrown. It also means that there is a serious disease, but you can not catch it from someone else who has it. The pathophysiological changes resulted in inflammation and symptoms such as coughing, wheezing and shortness of breath.

There are actually two types of asthma-extrinsic and internal. An asthma suffering from extrinsic asthma will have trouble with allergies and immune response. These individuals are often classified as being atopic dermatitis, which means they have trouble IgE response. People with asthma attacks internal factors means they are not immune either allergic to either aspirin or certain types of infections.

The common two are the individuals suffering from extrinsic asthma, or what is immune mediated. In these cases, the individual becomes inflamed lungs and bronchial tubes become hyper responsive to allergies. Inflammation of the airways is an important part of the pathology underlying the process of applying and keeps the inflammatory process.

inflammation activates the release of mast cells, eosinophils and macrophages in the airways. These compounds increase the amount of mucus present in the airways secretion.

The individual with asthma struggle with two individual responses of the bronchi and bronchioles leading to reduced air exchange in the lungs, coughing, wheezing and shortness of breath. First, the lungs become inflamed or swollen from allergic reactions to inhalation of the substance. The inflammation of one is enough to cause difficulty breathing, wheezing and shortness of breath.

Along with inflammation is increased mucus production caused by the body’s response to allergens inside the lungs. This increased mucus production also causes shortness of breath and wheezing but also causes coughing to clear mucus.

This complex interaction of inflammatory cells, mediators and tissue in the airways causing injury to epithelial and prolonged contraction of smooth muscle. Lungs continue to secrete mucus, swell and change control involuntary breathing. These swollen airways become narrow and prevent causing hyper-responsiveness and performance by reducing the stimulus is presented.

Individuals suffering from extrinsic asthma can be triggered by viral respiratory infections, pollen or mold, tobacco smoke, cold air, or even practice. Most must determine their specific calls in order to prevent them and thus prevent asthma attacks.

This airway obstruction can develop suddenly or gradually and will cause very real physical symptoms that can range from mild to life threatening. Although pressure has been known to increase the severity of symptoms, asthma is not a situation that is psychologically based. But, like all other physical illnesses, stress will increase the severity of the reactions to the disease.


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